What JUVEN Is and How It Can Help

Juven® is targeted nutrition therapy that contains a patented blend of arginine, glutamine and β-hydroxy-β-methylbutyrate (HMB). HMB may slow muscle breakdown by increasing protein synthesis, and arginine and glutamine are amino acids that support wound healing.

• HMB helps halt muscle breakdown and increase protein synthesis.1,2
• Arginine supports protein synthesis and improves nitrogen balance.3,4
• Glutamine enhances collagen and protein synthesis.5,6

Targeted nutrition therapy can help improve wound outcomes. Nutritional intervention that increases collagen and protein synthesis, supports immune function, and rebuilds lean body mass is a fundamental part of promoting wound healing.

Patients who may benefit from Juven are those with:

• Slow-healing wounds7 — those typically not healed in 30 days8
• Involuntary weight loss (IWL)9,10
• Deficient protein stores commonly seen in patients with IWL11,12

Wound Care Study Comparison 0.2MB)

Wound Outcomes Case Study (0.2MB)

References

1. Knitter AE, Panton L, Rathmacher JA, et al: J Appl Physiol 2000;89:1340-1344.
2. Smith HJ, Mukerji P, Tisdale MJ: Cancer Res 2005;65:277-283.
3. Kirk SJ, Hurson M, Regan MC, et al: Surgery 1993;114:155-160.
4. Pan M, Choudry HA, Epler MJ, et al: J Nutr 2004;134:2826S-2829S;discussion 28531-5.
5. Bellon G, Chaquor B, Wegrowski Y, et al: Biochim Biophys Acta 1995;1268:311-323.
6. Smith RJ: JPEN 1990;14:40S-44S.
7. US Department of Health and Human Services: AHCPR Pressure Ulcer Guidelines 1994.
8. Williams JZ, Abumrad N, Barbul A: Effect of a specialized amino acid mixture on human collagen deposition. Ann Surg 2002;236:369-375.
9. Bouras EP, Lange SM, Scolapio JS: Mayo Clin Proc 2001;76:923-929.
10. Galenos AN, Pieper CE, Kussin PS, et al: Crit Care Med 1997;25:1962-1968.
11. Rudman D, Feller AG, Nagraj HS, et al: JPEN 1987;11:360-363.
12. Hill GL: JPEN 1992;16:197-218.